Afkhami S, D’Agostino MR, Zhang A, Stacey HD, Marzok A, Kang A, Singh R, Bavananthasivam J, Ye G, Luo X, Wang F, Ang JC, Zganiacz A, Sankar U, Kazhdan N, Koenig JFE, Phelps A, Jordana M, Wan Y, Mossman KL, Jeyanathan M, Gillgrass A, Medina MFC, Smaill F, Lichty BD, Miller MS, Xing Z. Single-dose respiratory mucosal delivery of next-generation viral-vectored COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2. doi: https://doi.org/10.1101/2021.07.16.452721. *Pre-print

 

Gillgrass A, Wessels JM, Yang JX, Kaushic C. Advances in Humanized Mouse Models to Improve Understanding of HIV-1 Pathogenesis and Immune Responses. Frontiers in Immunology. 2021 Mar 5;11:617516. doi.org/10.3389/fimmu.2020.617516

 

Singh R, Kang A, Luo X, Jeyanathan M, Gillgrass A, Afkhami S, Xing Z. COVID-19: Current knowledge in clinical features, immunological responses, and vaccine development. The FASEB Journal. 2021 Mar;35(3):e21409. doi: 10.1096/fj.202002662R.

 

Afkhami S, Villela AD, D'Agostino MR, Jeyanathan M, Gillgrass A, Xing Z. Advancing Immunotherapeutic Vaccine Strategies Against Pulmonary Tuberculosis. Front Immunol. 2020 Sep 9;11:557809. doi: 10.3389/fimmu.2020.557809.

 

Shenouda MM, Gillgrass A, Nham T, Hogg R, Lee AJ, Chew MV, Shafaei M, Aarts C, Lee DA, Hassell J, Bane A, Dhesy-Thind S, Ashkar AA. Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours. Breast Cancer Res. 2017 Jul 1;19(1):76. doi: 10.1186/s13058-017-0867-9.

 

Krneta T, Gillgrass A, Poznanski S, Chew M, Lee AJ, Kolb M, Ashkar AA. M2-polarized and tumor-associated macrophages alter NK cell phenotype and function in a contact-dependent manner. J Leukoc Biol. 2017 Jan;101(1):285-295. doi: 10.1189/jlb.3A1215-552R.

 

Cockburn JG, Hallett RM, Gillgrass AE, Dias KN, Whelan T, Levine MN, Hassell JA, Bane A. The effects of lymph node status on predicting outcome in ER+ /HER2- tamoxifen treated breast cancer patients using gene signatures. BMC Cancer. 2016 Jul 28;16:555. doi: 10.1186/s12885-016-2501-0.

 

Krneta T, Gillgrass A, Chew M, Ashkar AA. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016 Sep;13(5):628-39. doi: 10.1038/cmi.2015.42.

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Gillgrass A, Chew MV, Krneta T, Ashkar AA. Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model. BMC Cancer. 2015 Apr 16;15:293. doi: 10.1186/s12885-015-1264-3.

 

Barra NG, Palanivel R, Denou E, Chew MV, Gillgrass A, Walker TD, Kong J, Richards CD, Jordana M, Collins SM, Trigatti BL, Holloway AC, Raha S, Steinberg GR, Ashkar AA. Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. PLoS One. 2014 Dec 17;9(12):e114799. doi: 10.1371/journal.pone.0114799.

 

Gillgrass A, Gill N, Babian A, Ashkar AA. The absence or overexpression of IL-15 drastically alters breast cancer metastasis via effects on NK cells, CD4 T cells, and macrophages. J Immunol. 2014 Dec 15;193(12):6184-91. doi: 10.4049/jimmunol.1303175.

 

Chu DK, Mohammed-Ali Z, Jiménez-Saiz R, Walker TD, Goncharova S, Llop-Guevara A, Kong J, Gordon ME, Barra NG, Gillgrass AE, Van Seggelen H, Khan WI, Ashkar AA, Bramson JL, Humbles AA, Kolbeck R, Waserman S, Jordana M. T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes. Mucosal Immunol. 2014 Nov;7(6):1395-404. doi: 10.1038/mi.2014.29.

 

Krneta T, Gillgrass A, Ashkar AA. The influence of macrophages and the tumor microenvironment on natural killer cells. Curr Mol Med. 2013 Jan;13(1):68-79. PMID: 22834841.

 

Roth KL, Bhavanam S, Jiang H, Gillgrass A, Ho K, Ferreira VH, Kaushic C. Delayed but effective induction of mucosal memory immune responses against genital HSV-2 in the absence of secondary lymphoid organs. Mucosal Immunol. 2013 Jan;6(1):56-68. doi: 10.1038/mi.2012.48.

 

Abdul-Careem MF, Mian MF, Yue G, Gillgrass A, Chenoweth MJ, Barra NG, Chew MV, Chan T, Al-Garawi AA, Jordana M, Ashkar AA. Critical role of natural killer cells in lung immunopathology during influenza infection in mice. J Infect Dis. 2012 Jul 15;206(2):167-77. doi: 10.1093/infdis/jis340.

 

Abdul-Careem MF, Lee AJ, Pek EA, Gill N, Gillgrass AE, Chew MV, Reid S, Ashkar AA. Genital HSV-2 infection induces short-term NK cell memory. PLoS One. 2012;7(3):e32821. doi: 10.1371/journal.pone.0032821.

 

Abdul-Careem MF, Firoz Mian M, Gillgrass AE, Chenoweth MJ, Barra NG, Chan T, Al-Garawi AA, Chew MV, Yue G, van Roojen N, Xing Z, Ashkar AA. FimH, a TLR4 ligand, induces innate antiviral responses in the lung leading to protection against lethal influenza infection in mice. Antiviral Res. 2011 Nov;92(2):346-55. doi: 10.1016/j.antiviral.2011.09.004.

 

Gillgrass A, Ashkar A. Stimulating natural killer cells to protect against cancer: recent developments. Expert Rev Clin Immunol. 2011 May;7(3):367-82. doi: 10.1586/eci.10.102.

 

Barra NG, Gillgrass A, Ashkar AA. Effective control of viral infections by the adaptive immune system requires assistance from innate immunity. Expert Rev Vaccines. 2010 Oct;9(10):1143-7. doi: 10.1586/erv.10.119.

 

Gillgrass A, Chege D, Bhavanam S, Kaushic C. Estradiol limits viral replication following intravaginal immunization leading to diminished mucosal IgG response and non-sterile protection against genital herpes challenge. Am J Reprod Immunol. 2010 Apr 1;63(4):299-309. doi: 10.1111/j.1600-0897.2009.00796.x.

 

MacDonald EM, Savoy A, Gillgrass A, Fernandez S, Smieja M, Rosenthal KL, Ashkar AA, Kaushic C. Susceptibility of human female primary genital epithelial cells to herpes simplex virus, type-2 and the effect of TLR3 ligand and sex hormones on infection. Biol Reprod. 2007 Dec;77(6):1049-59. doi: 10.1095/biolreprod.107.063933.

 

Fernandez S, Gillgrass A, Kaushic C. Differential responses of murine vaginal and uterine epithelial cells prior to and following herpes simplex virus type 2 (HSV-2) infection. Am J Reprod Immunol. 2007 May;57(5):367-77. doi: 10.1111/j.1600-0897.2007.00482.x.

 

Gillgrass AE, Tang VA, Towarnicki KM, Rosenthal KL, Kaushic C. Protection against genital herpes infection in mice immunized under different hormonal conditions correlates with induction of vagina-associated lymphoid tissue. J Virol. 2005 Mar;79(5):3117-26. doi: 10.1128/JVI.79.5.3117-3126.2005.

 

Gillgrass AE, Fernandez SA, Rosenthal KL, Kaushic C. Estradiol regulates susceptibility following primary exposure to genital herpes simplex virus type 2, while progesterone induces inflammation. J Virol. 2005 Mar;79(5):3107-16. doi: 10.1128/JVI.79.5.3107-3116.2005.

 

Gillgrass A, Cardiff RD, Sharan N, Kannan S, Muller WJ. Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression. Oncogene. 2003 Dec 11;22(57):9151-5. doi: 10.1038/sj.onc.1206983.

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Gillgrass AE, Ashkar AA, Rosenthal KL, Kaushic C. Prolonged exposure to progesterone prevents induction of protective mucosal responses following intravaginal immunization with attenuated herpes simplex virus type 2. J Virol. 2003 Sep;77(18):9845-51. doi: 10.1128/jvi.77.18.9845-9851.2003.

 

Rosner A, Miyoshi K, Landesman-Bollag E, Xu X, Seldin DC, Moser AR, MacLeod CL, Shyamala G, Gillgrass AE, Cardiff RD. Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors. Am J Pathol. 2002 Sep;161(3):1087-97. doi: 10.1016/S0002-9440(10)64269-1.